diff --git a/configs/tfm_mbedcrypto_config_profile_medium.h b/configs/tfm_mbedcrypto_config_profile_medium.h
index 41e3afe273..88736b54bb 100644
--- a/configs/tfm_mbedcrypto_config_profile_medium.h
+++ b/configs/tfm_mbedcrypto_config_profile_medium.h
@@ -456,45 +456,6 @@
  */
 #define MBEDTLS_MEMORY_BUFFER_ALLOC_C
 
-/**
- * \def MBEDTLS_PK_C
- *
- * Enable the generic public (asymetric) key layer.
- *
- * Module:  library/pk.c
- *
- * Requires: MBEDTLS_RSA_C or MBEDTLS_ECP_C
- *
- * Uncomment to enable generic public key wrappers.
- */
-#define MBEDTLS_PK_C
-
-/**
- * \def MBEDTLS_PK_PARSE_C
- *
- * Enable the generic public (asymetric) key parser.
- *
- * Module:  library/pkparse.c
- *
- * Requires: MBEDTLS_PK_C
- *
- * Uncomment to enable generic public key parse functions.
- */
-#define MBEDTLS_PK_PARSE_C
-
-/**
- * \def MBEDTLS_PK_WRITE_C
- *
- * Enable the generic public (asymetric) key writer.
- *
- * Module:  library/pkwrite.c
- *
- * Requires: MBEDTLS_PK_C
- *
- * Uncomment to enable generic public key write functions.
- */
-#define MBEDTLS_PK_WRITE_C
-
 /**
  * \def MBEDTLS_PLATFORM_C
  *